N-butyryl-L-Homoserine lactone

Synonyms	C4-HSL N-butyryl-L-Homoserine Butyryl-L-hoMoserine lactone N-butyryl-L-Homoserine lactone N-(2-oxotetrahydrofuran-3-yl)butanamide (S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
CAS	67605-85-0

Molecular Formula	C8H13NO3
Molar Mass	171.195
Density	1.13
Melting Point	120-123 °C
Boling Point	428.1±34.0 °C(Predicted)
Solubility	Chloroform (Sparingly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
pKa	14.78±0.20(Predicted)
Storage Condition	2-8°C
In vitro study	The dissociation constant (K d value) of aptamer binding to N-Butanoyl-L-homoserine lactone (C4-HSL) is 28.47 nM.

biological activity	N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker, for the synthesis of antibody-conjugated drugs (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity, can be used for antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers can be used to prevent quorum sensing and inhibit the formation of Pseudomonas aeruginosa biofilm.
Target	Cleavable
in vitro study	The dispersion constant (K d value) of aptamer binding to N-Butanoyl-L-homoserine lactone (C4-HSL) is 28.47 nM.

Last Update：2024-04-09 20:49:11